The Sigmoid (S-Shaped) Binding Curve That Describes the Interaction of O₂

question 35

Multiple Choice

The sigmoid (S-shaped) binding curve that describes the interaction of O₂ with hemoglobin is a direct consequence of

• A) allosteric regulation by 2,3-bisphosphoglycerate.
• B) cooperativity among subunits.
• C) covalent bonds between alpha beta?heterodimers.
• D) orientation of histidine residues near the heme groups.
• E) reversible oxidation and reduction of heme iron atoms.

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