Which of the Following Statements About the Interaction of Heme

question 2

Multiple Choice

Which of the following statements about the interaction of heme units of hemoproteins with oxygen is correct?

• A) Binding of 2,3-bisphosphoglycerate (BPG) to hemoglobin leads to increased binding of oxygen.
• B) Binding of oxygen to one myoglobin increases the strength of binding of oxygen to other myoglobins.
• C) In blood of peripheral tissues, the loss of an oxygen by a heme unit is balanced stoichiometrically by the loss of one hydrogen.
• D) The binding of oxygen by separated beta-chains of hemoglobin is described by a sigmoid curve.
• E) As oxygen binds to hemoglobin, the pKa's of certain amino acid sidechains decrease.

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