In the Presence of a Typical Noncompetitive Inhibitor of the Activity

question 91

Multiple Choice

In the presence of a typical noncompetitive inhibitor of the activity of a particular enzyme toward a given substrate

• A) the enzyme is irreversibly inactivated.
• B) the potential maximum velocity will remain unchanged from that in the absence of the inhibitor.
• C) the interaction of the inhibitor with the substrate is a major factor leading to the inhibition observed.
• D) sigmoidal kinetics would be expected if there is no change in protein conformation on the binding of either S or I.
• E) the apparent Michaelis constant for the substrate will be the same with or without inhibitor present.

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