Koshland Has Proposed the Induced Fit Theory of Enzyme Action

question 69

Multiple Choice

Koshland has proposed the induced fit theory of enzyme action. This concept implies that:

• A) the template or lock-and-key theory adequately explains the mechanism of enzyme catalysis.
• B) the active site is flexible; the catalytic group(s) of the enzyme is/are brought into proper alignment by the substrate.
• C) the conformation of the substrate changes before binding to the enzyme.
• D) the formation of the enzyme-substrate complex is always the fastest step in an enzyme catalyzed reaction.

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