The Toxic Form of Benzoapyrene Binds Covalently to DNA

question 3

Multiple Choice

The toxic form of benzoapyrene binds covalently to DNA. What mechanism does benzoapyrene use to potentiate its toxicity?

• A) It binds covalently to cytochrome P450
• B) It increases the amount of AhR
• C) It induces cytochrome P450 and its own metabolism
• D) It inhibits glucuronidation
• E) It inhibits its own further metabolism

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