Certain Bacterial Exotoxins, Such as Cholera and Pertussis, Are Useful

question 35

Multiple Choice

Certain bacterial exotoxins, such as cholera and pertussis, are useful in defining the steps and proteins in signal transduction pathways. Which of the following reactions best accounts for this toxin property?

• A) activation of specific lipid kinases
• B) covalent modification of heterotrimeric G proteins
• C) high?affinity binding to nuclear receptors
• D) inhibition of cyclic nucleotide hydrolysis
• E) rapid release of Ca²⁺ into cytosol

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