Why Is the Hydrolysis of GTP by a G-Protein Essentially

question 17

Multiple Choice

Why is the hydrolysis of GTP by a G-protein essentially irreversible?

• A) GDP immediately hydrolyzes to GMP and Pi
• B) GDP is metabolized to cGMP
• C) GDP remains bound after Pi is liberated
• D) GTP cannot be synthesized from GDP
• E) The Km for Pi is too low

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