Glucocorticoids Such as Cortisol and Corticosterone Have Distinct Effects on Hepatic

question 48

Multiple Choice

Glucocorticoids such as cortisol and corticosterone have distinct effects on hepatic carbohydrate metabolism, such as promoting gluconeogenesis and glycogen deposition. The likely mechanism of these effects involves

• A) binding of glucocorticoids to liver cell membrane receptors with concomitant activation of adenylate cyclase.
• B) acute stimulation of enzymes in the pathways of gluconeogenesis and glycogenesis.
• C) direct inhibition of enzymes participating in glycolysis and glycogenesis.
• D) induction of new enzyme synthesis for enzymes in the pathways of gluconeogenesis and glycogen synthesis.

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