The Inhibition of the Synthesis of DNA by Methotrexate Results

question 50

Multiple Choice

The inhibition of the synthesis of DNA by methotrexate results from direct inhibition of

• A) a reaction in the pathway of purine biosynthesis.
• B) thymidylate synthase.
• C) the reduction of ribonucleotides to deoxyribonucleotides.
• D) synthesis of S-adenosylmethionine.
• E) the reduction of dihydrofolate to tetrahydrofolate.

---

Definitions:

Nature

All aspects of the material world such as animals, plants, landscapes, and earth's own creations, excluding human-made objects and structures.

Nurture

The process of caring for and encouraging the growth or development of someone or something, often emphasizing the environmental influences on development.

Authoritative

Pertaining to a style of parenting or leadership that is firm, fair, and nurturing, balancing demands with responsiveness.

Demanding

Requiring much time, effort, or attention, often in a way that is challenging or strenuous.