Suppose That You Are a Genetic Counsellor, and a Couple

question 68

Multiple Choice

Suppose that you are a genetic counsellor, and a couple comes to you with concerns that if they have a child together, it could have hemophilia. Suppose also that neither one of them has hemophilia, but the woman's biological father did have an X-linked recessive form of hemophilia. Which of the following is the best advice you could give them?

• A) Each of their male offspring will have hemophilia, and each of their female offspring will have a 50% chance of having hemophilia.
• B) None of their offspring should have hemophilia, but each of their female offspring will be carriers for hemophilia.
• C) Each child that they produce will have a 50% chance of having hemophilia.
• D) Each of their male offspring will have a 50% chance of having hemophilia, and while their female offspring should not have hemophilia, they will each have a 50% chance of being carriers.

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