Use the Following to Answer Questions

question 7

Multiple Choice

Use the following to answer questions
Scenario I
The following scenario is based on and presents fabricated data consistent with the following study:
Caspi,A. ,Sugden,K. ,Moffitt,T.E. ,Taylor,A. ,Craig,I.W. ,Harrington,H. ,McClay,J. ,Mill,J. ,Martin,J. ,Braithwaite,A. ,and Poulton,R.(2003) .Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene.Science,301(5631) ,386-389.
The serotonin transporter gene codes for the serotonin transporter,a protein that transports serotonin from the synapse to the presynaptic neuron.Several polymorphisms of the gene exist,including a "short" (s) and a "long" (l) variation.As humans receive one copy of the gene from each parent,people can be grouped into three groups based on this genetic variation: s/s (two copies of the short gene) ,s/l,and l/l.Caspi et al.(2003) interviewed participants in each of these groups and asked them a wide range of questions to determine both the degree of exposure to stress and the number of depressive episodes participants had experienced in their lives.Fabricated results consistent with their major findings are shown in Figure 3.1.
Figure 3.1
-(Scenario I) An individual has two copies of the small variation of the serotonin transporter gene and has been exposed to a high degree of stress over the course of her lifetime.Based on the results shown in the scenario,one could:

• A)accurately predict that the person probably has experienced an episode of major depression at least once in her life.
• B)accurately predict that the person is currently depressed.
• C)justify prescribing antidepressant drugs to the individual.
• D)conclude that the person carries a risk factor for depression.

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