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Cocaine Addiction
A chronic, relapsing disease characterized by a compulsion to seek and use cocaine, despite detrimental consequences.
Spine Density
Refers to the number of dendritic spines (small protrusions on dendrites where synapses are located) per unit length of dendrite, indicating the potential for synaptic connectivity.
Prefrontal Cortex
The frontal part of the frontal lobe of the brain, involved in complex behaviors including planning, decision making, and moderating social behavior.
Behavioral Sensitization
Escalating behavioral response to the repeated administration of a psychomotor stimulant such as amphetamine, cocaine, or nicotine; also called drug-induced behavioral sensitization.
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