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Compared with a pure agonist,a mixed agonist-antagonist in drug-naive subjects has:
Genetic Differences
Genetic differences are variations in the sequences of DNA among individuals or populations, leading to diversity in traits and susceptibilities to diseases.
Genetic Variation
The diversity in gene frequencies within a population, which contributes to the population's ability to adapt and evolve.
Additive Effects
The combined effect of different genes, where the overall effect is the sum of the individual effects of each gene.
Phenotypic Plasticity
Phenotypic plasticity refers to changes in the phenotype produced by a single genotype in different environments.
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