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A frequent drug user finds that larger doses of a drug are necessary to produce the same "high" that much lower doses once produced. That drug user is developing:
Veins
Blood vessels that carry blood toward the heart, typically carrying deoxygenated blood from the tissues back to the heart except in the case of pulmonary veins.
Hemostasis
The physiological process by which bleeding ceases, involving blood vessel constriction and clot formation.
Thrombin
An enzyme in blood plasma that causes the clotting of blood by converting fibrinogen to fibrin.
Systole
Contractile phase of the cardiac cycle.
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