Which of the Following Is a Likely Mechanism for Long-Term

question 129

Multiple Choice

Which of the following is a likely mechanism for long-term potentiation?

• A) When glutamate binds to postsynaptic AMPA receptors, it activates intracellular changes.
• B) When glutamate binds to NMDA receptors, it allows magnesium ions to enter the cell, which initiate intracellular changes.
• C) When sufficient glutamate is released by the presynaptic neuron, it dislodges Mg²⁺ from the AMPA receptors and allows Ca²⁺ to leave the cell.
• D) When sufficient glutamate is released, both AMPA and NMDA receptors are activated, and NMDA receptors allow Ca²⁺ as well as Na⁺ to enter the cell, thus initiating intracellular changes.
• E) When both glutamate and ACh are released together, they create a long-lasting depolarization of the postsynaptic cell.

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