You Have Characterized Over 100 Mutations in a Partic-Ular Gene

question 14

Essay

You have characterized over 100 mutations in a partic-ular gene that are linked to a certain disease. The mutations you have identified are all due to a single base change in one codon of the gene encoding protein X. Which DNA technique would you use to analyze patients who might have this disease?

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Definitions:

Alveoli

Small air pockets in the lungs where oxygen and carbon dioxide are exchanged.

Epithelium

A layer of cells covering the body surfaces, lining cavities, and forming glandular tissue.

Larynx

The hollow muscular organ forming an air passage to the lungs and holding the vocal cords; also known as the voice box.

Pharynx

The muscular tube in humans and other vertebrates connecting the mouth and nasal cavities to the esophagus and larynx; plays a key role in swallowing and breathing.