What Would Be the Effect of a Deletion of the DNA

question 29

Essay

What would be the effect of a deletion of the DNA encoding the targeting sequence for that gene product? (Imagine that this protein was targeted to go to the endoplasmic reticulum and the signal sequence was removed as a result of this deletion.)

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Definitions:

Antidiuretic Hormone

A hormone released by the pituitary gland that helps regulate the body's retention of water by increasing the reabsorption of water in the kidneys.

Aldosterone Release

The secretion of aldosterone, a hormone regulating sodium and potassium levels, from the adrenal gland.

Metabolic Acidosis

A condition characterized by an excess of acid in the body, due to the accumulation of acid or depletion of alkaline reserves.

Kussmaul Breathing

A deep and labored breathing pattern often associated with severe metabolic acidosis, particularly diabetic ketoacidosis.