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Suppose That Two Auxotrophic Mutants That Had Been Isolated Are

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Suppose that two auxotrophic mutants that had been isolated are able to grow when fed the same biochemical intermediate. According to the experiments of Beadle and Tatum, the mutations in each of these auxotrophs should be in the same gene, because they were blocked at the same step in a biochemical pathway. Yet, these two auxotrophs had mutations that mapped in different genes. How do you explain this?


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