Based on your knowledge of electrophilic aromatic substitution,and assuming the thiophene ring of benzo[b]thiophene (shown)is activated toward electrophilic aromatic substituted more so than the benzenoid ring,predict the preferential position of attack of an electrophile,i.e.,does the electrophile E+ attack carbon 2,or 3? Explain your answer. ![Based on your knowledge of electrophilic aromatic substitution,and assuming the thiophene ring of benzo[b]thiophene (shown)is activated toward electrophilic aromatic substituted more so than the benzenoid ring,predict the preferential position of attack of an electrophile,i.e.,does the electrophile E<sup>+</sup> attack carbon 2,or 3? Explain your answer. Which substitution product forms preferentially and why?](https://d2lvgg3v3hfg70.cloudfront.net/TB5902/11eaa4bc_3e00_d406_9180_99e4e81ed72e_TB5902_00.jpg)
Which substitution product forms preferentially and why?
Definitions:
pre-mRNAs
The precursor mRNA transcripts that are synthesized from DNA and contain both introns and exons, which are modified and spliced to form mature mRNA.
Phosphate Group
A functional group consisting of a phosphorus atom covalently bonded to four oxygen atoms, important in energy transfer and storage.
Promoter Sequence
A specific region of DNA upstream of a gene that binds RNA polymerase and initiates transcription of the gene.
Transcription
The process of copying a segment of DNA into RNA by the enzyme RNA polymerase.
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