Which One Is the Correct Reaction Sequence for the Attachment

question 96

Multiple Choice

Which one is the correct reaction sequence for the attachment of valine on the N-terminus of a growing peptide?

• A)Amino group deprotection,addition of Val and base,heating.
• B)Amino group cleavage on Val,activation of carboxylic acid functionality on growing peptide chain,reaction between the two.
• C)Amino group protection on the growing peptide chain,activation of the carboxylic acid functionality on Val,reaction with growing peptide.
• D)Amino group deprotection on growing peptide,activation of the carboxylic acid functionality on Val,reaction with growing peptide.
• E)Mix Val and growing peptide,add base and incubate the two for a period of time.

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