In the Synthesis of Cytidine (Bz Protected),the Amino Group at Position

question 91

Multiple Choice

In the synthesis of cytidine (Bz protected) ,the amino group at position 4 (N⁴) of cytosine is protected with a benzoyl protecting group because

• A)the primary amino group would react faster than the secondary N¹.
• B)The cytosine reagent would not be soluble in the reaction medium.
• C)Cytosine needs to be activated with the benzoyl protecting group.
• D)The amino group needs to remain protected after hydrolysis of benzoyl groups.
• E)The activation of the primary is needed for the reaction with the d-ribose.

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