The Suggested Mechanism of Catalysis for the Peptide Bond Formation $\alpha$

question 59

Multiple Choice

The suggested mechanism of catalysis for the peptide bond formation during protein synthesis involves

• A)a guanine group that produces acid-base catalysis in the attack of the amino group of one amino acid to the carboxylic acid function of the other.
• B)an acid-base catalysis effected by a glutamic acid in the RNA during the nucleophilic attack of the amino group on the acyl carbon of the peptide.
• C)A tetrahedral intermediate formed by the attack of a base from the tRNA on the \(\alpha\)-amino group of the incoming amino acid.
• D)a total or partial removal of a proton on the \(\alpha\)-amino group of an amino acid facilitating the attack on the acyl carbon of the growing peptide on the tRNA.
• E)a nucleophilic attack of an adenine on the \(\alpha\)-amino group of the incoming amino acid.

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