The Automated Synthesis of Oligonucleotides

question 22

Multiple Choice

The automated synthesis of oligonucleotides

• A)Uses dimethoxytrityl resin as solid phase.
• B)Is done in solution phase; the precipitated product is isolated by filtration.
• C)Is done in solid phase using an exchange resin and phosphoramidite monomers.
• D)Uses controlled pore glass as solid phase and phosphoramidite monomers.
• E)Is done in solution phase on a type of glass container that catalyzes the reaction.

---

Definitions:

Average Accounting Return

The ratio of average net income to average invested capital, often used in financial analysis to assess investment attractiveness.

Profitability Index

A financial metric that calculates the ratio of the present value of future cash flows from an investment to the initial investment cost, used to evaluate the desirability of projects.

Present Value

Present value refers to the current value of a future amount of money or series of cash flows, calculated using a specific rate of return.

Net Present Value

A calculation used to assess the profitability of an investment, considering the difference between the present value of cash inflows and outflows over a period of time.