The Folding Cycle in the GroES-GroEL Complex of E

question 34

Multiple Choice

The folding cycle in the GroES-GroEL complex of E. coli utilizes the following sequence:
A.ATP binding to GroEL
B.GroES dissociates from the complex
C.Partially folded protein hydrophobic residues bind GroEL
D.GroES is recruited to GroEL
E.GroES promotes ATP hydrolysis and α-subunits undergo a conformational change that buries the hydrophobic patches

• A) A, B, C, D, E
• B) B, A, C, D, E
• C) C, D, A, E, B
• D) C, A, D, E, B
• E) D, C, E, A, B

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Definitions:

Confounding Assignment

A situation in research where a variable other than the independent variable is potentially influencing the outcome of the study, making it difficult to isolate the effect of the independent variable.

Selective Assignment

Refers to a process or strategy where tasks, roles, or responsibilities are assigned to individuals based on specific criteria or attributes.

Many Labs Approach

When different groups of researchers do the exact same study at the same time.

Meta-Analysis

A study that statistically analyzes the results of many studies on the same topic.