In Order for Transcription to Begin, the DNA-Duplex Must Be

question 9

Multiple Choice

In order for transcription to begin, the DNA-duplex must be "opened" to allow RNA polymerase access to single stranded template. All facilitate "opening" of DNA-duplex EXCEPT:

• A) low melting temperature, T_m, in the Pribnow box.
• B) A:T rich DNA duplex.
• C) negative supercoiling.
• D) binding of RNA polymerase σ-subunit.
• E) all are true.

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