Enzymatic Ribonucleotide Reduction Is Accomplished Via a Free Radical Mechanism

question 28

Multiple Choice

Enzymatic ribonucleotide reduction is accomplished via a free radical mechanism. Which of the following statements is true regarding this process?

• A) The substrate specificity site on the R1 homodimer determines if the enzyme is active or inactive.
• B) R2 has a single active site containing two Fe atoms that generate the free radicals required for reduction.
• C) R2, but not R1, function in the delivery of reducing equivalents.
• D) R2 homodimer carries two regulatory sites.
• E) A final decarboxylation forms the deoxyribonucleotide product.

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