Glutamine Phosphoribosyl Pyrophosphate Amidotransferase Catalyzes Step 2 in the Biosynthesis

question 15

Multiple Choice

Glutamine phosphoribosyl pyrophosphate amidotransferase catalyzes step 2 in the biosynthesis of purines. Which of the following is a true statement regarding the regulation of this enzyme?

• A) It is accelerated by an input of ATP or GTP.
• B) It is sensitive to activation by azaserine.
• C) It is accelerated by an input of AMP or GMP.
• D) The G series of nucleotides as well as the adenine nucleotides act as competitive inhibitors.
• E) It is subject to feed-forward activation by ADP.

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