Polylysine Is a Random Coil When the PH Is Less

question 30

Multiple Choice

Polylysine is a random coil when the pH is less than 11, while it forms an α-helix if the pH is raised to greater than 12. This is because at pH 12:

• A) the lysine residues are negatively charged which electrostatically stabilizes the helix.
• B) the positive charges on the lysine residues stabilizes the α-helix.
• C) the lysine residues are neutral which eliminates electrostatic repulsion between the R groups.
• D) the high concentration of OH− ions in solution reduces the electrostatic repulsion between the R-groups.
• E) the lysine side chain changes configuration with pH.

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