Which of the Following Statements About the Proposed Mechanisms of Action

question 5

Multiple Choice

Which of the following statements about the proposed mechanisms of action for hen egg white lysozyme does NOT support either model?

• A) Glycosidic bond cleavage occurs by general acid/base catalysis.
• B) A covalent intermediate is formed between an active site aspartate and C1 of the substrate.
• C) A water molecule is deprotonated, which then attacks C1 of the substrate.
• D) The active site aspartic acid changes between being protonated and deprotonated.
• E) The active site glutamic acid changes between being protonated and deprotonated.