Which of the Following Is NOT Correct When Considering the Initiation

question 2

Multiple Choice

Which of the following is NOT correct when considering the initiation of transcription in E. coli?

• A) The σ subunit of RNA polymerase makes strong contacts with the -10 region of promoters.
• B) Only the -10 region of the promoter is required.
• C) DNA melting near the transcription start site is essential for promoter recognition.
• D) The phosphodiester bonds that are formed are not stable until about 10 nucleotides have been incorporated.
• E) The RNA polymerase contacts about 50 bp of DNA.

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