Which of the Following Statements About E

question 5

Multiple Choice

Which of the following statements about E. coli DNA replication is INCORRECT?

• A) The β subunit of DNA polymerase III is the sliding clamp essential for processivity.
• B) The clamp-loading complex uses exchange between ADP and ATP to eject the clamp loader and close the clamp.
• C) Single-stranded DNA-binding protein promotes denaturation of DNA by lowering the melting temperature.
• D) Helicases are multimeric proteins that bind preferentially to one strand and rely on ATP-hydrolysis to unwind the duplex.
• E) Topoisomerases are responsible for relieving torsional stress ahead of the replication fork generated by unwinding the duplex.

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