Lethal Genes (Genes That Result in the Failure to Develop

question 44

Multiple Choice

Lethal genes (genes that result in the failure to develop a vital organ or metabolic pathway) are nearly always recessive. Animal breeders who discover a unique trait and selectively breed to increase the occurrence of that trait often encounter a noticeable increase in lethal genes. Why?

• A) The lethal recessive gene may be incompletely dominant.
• B) Spreading the gene among offspring of both sexes will increase the likelihood it will be sex-linked and expressed.
• C) The selective-mating of closely related individuals, or inbreeding, increases chances that two recessive genes will "meet" in offspring.
• D) "Pleiotropy" - the gene that is being selected for this trait may have the second effect of being lethal.
• E) "Epistasis" - selection for the desired trait may result in "uncovering" the lethal gene.

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