If Patients with Advanced CML Are Initially Treated with Gleevec,they

question 12

Multiple Choice

If patients with advanced CML are initially treated with Gleevec,they generally develop resistance to the drug within a few months.What seems to cause the resistance?

• A)mutations in the BCR portion of the fusion gene
• B)mutations in the ABL portion of the fusion gene
• C)ABL gene deletion
• D)ABL gene amplification
• E)BCR gene amplification

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Definitions:

Neuroscience Approach

A method of studying the nervous system to understand the biological bases of behavior, cognition, and emotion.

Apraxia

A motor disorder caused by damage to the brain, characterized by difficulty in executing purposeful movements despite having the desire and physical ability to perform them.

Aphasia

is a communication disorder that results from damage to parts of the brain responsible for language, affecting the person's ability to speak, write, and understand others.

Agnosia

A neurological disorder marked by the inability to recognize and identify objects, people, sounds, or shapes, despite intact sensory faculties.