What Are the Differences Between PiRNAs on the One Hand

question 35

Multiple Choice

What are the differences between piRNAs on the one hand and si/miRNAs on the other hand?

• A)piRNAs are longer than si/miRNAs.
• B)The majority of mammalian piRNAs can be mapped to a small number of huge genomic loci,unlike si/mi RNAs.
• C)The formation of piRNAs does not involve the formation of dsRNA precursors,unlike si/mi RNAs.
• D)Formation of piRNAs does not involve cleavage by Dicer ribonuclease,but instead it depends on the endonuclease activity of the PIWI protein acting on a long,single stranded primary transcript.
• E)All of these are correct.

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Definitions:

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