You Are Investigating the Interactions of Integrin $\alpha$ And $\beta$ Subunits and Isolate the Extracellular Portion of an Integrin as Subunits

question 89

Multiple Choice

You are investigating the interactions of integrin $\alpha$ and $\beta$ subunits and isolate the extracellular portion of an integrin as a soluble $\alpha$ / $\beta$ heterodimer.The heterodimer lacks the associated transmembrane and cytoplasmic domains normally present as part of the molecule.You experimentally link the $\alpha$ and $\beta$ subunits at the bases of their legs so that the ligand-binding regions of the $\alpha$ and $\beta$ subunits approach one another.Which of the following statements is true about the molecules formed?

• A)The molecules bind their ligand tightly.
• B)The molecules are unable to bind a ligand.
• C)The molecules are cleaved.
• D)The molecules denature their ligand.
• E)The molecules denature and degrade.

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Definitions:

GAAS Auditing

Standards that guide the conduct of audits on the financial statements of companies, known as Generally Accepted Auditing Standards.

Adverse Opinion

An auditor’s opinion that states that deviations from generally accepted accounting principles are so serious that an unqualified opinion is impossible and a qualified opinion is not justified.

GAAP

Generally Accepted Accounting Principles; the standard framework of guidelines for financial accounting used in any given jurisdiction.

FASB

Stands for Financial Accounting Standards Board, an organization responsible for establishing accounting and financial reporting standards for companies and non-profit organizations in the United States.