You Are Investigating the Interactions of Integrin $\alpha$ And $\beta$ Subunits and Isolate the Extracellular Portion of an Integrin as Subunits

question 89

Multiple Choice

You are investigating the interactions of integrin $\alpha$ and $\beta$ subunits and isolate the extracellular portion of an integrin as a soluble $\alpha$ / $\beta$ heterodimer.The heterodimer lacks the associated transmembrane and cytoplasmic domains normally present as part of the molecule.You experimentally link the $\alpha$ and $\beta$ subunits at the bases of their legs so that the ligand-binding regions of the $\alpha$ and $\beta$ subunits approach one another.Which of the following statements is true about the molecules formed?

• A)The molecules bind their ligand tightly.
• B)The molecules are unable to bind a ligand.
• C)The molecules are cleaved.
• D)The molecules denature their ligand.
• E)The molecules denature and degrade.

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Definitions:

Homosexual Males

Men who are emotionally, romantically, or sexually attracted to other men.

Heterosexual Males

Men who are sexually attracted to women.

Brain Structure

The physical configuration and anatomical components of the brain, including various regions, lobes, and neural pathways.

Androgyny

A blend of both masculine and feminine characteristics or a state of gender ambiguity.