You Are Investigating the Interactions of Integrin $\alpha$ And $\beta$ Subunits and Isolate the Extracellular Portion of an Integrin as Subunits

question 89

Multiple Choice

You are investigating the interactions of integrin $\alpha$ and $\beta$ subunits and isolate the extracellular portion of an integrin as a soluble $\alpha$ / $\beta$ heterodimer.The heterodimer lacks the associated transmembrane and cytoplasmic domains normally present as part of the molecule.You experimentally link the $\alpha$ and $\beta$ subunits at the bases of their legs so that the ligand-binding regions of the $\alpha$ and $\beta$ subunits approach one another.Which of the following statements is true about the molecules formed?

• A)The molecules bind their ligand tightly.
• B)The molecules are unable to bind a ligand.
• C)The molecules are cleaved.
• D)The molecules denature their ligand.
• E)The molecules denature and degrade.

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