If Patients with Advanced CML Are Initially Treated with Gleevec,they

question 12

Multiple Choice

If patients with advanced CML are initially treated with Gleevec,they generally develop resistance to the drug within a few months.What seems to cause the resistance?

• A)mutations in the BCR portion of the fusion gene
• B)mutations in the ABL portion of the fusion gene
• C)ABL gene deletion
• D)ABL gene amplification
• E)BCR gene amplification

---

Definitions:

Bounded Rationality

A concept that suggests individuals make decisions based on a limited amount of information and cognitive constraints.

Rational Choice

is a theory that assumes individuals make decisions based on the maximization of personal advantage, weighing benefits against costs.

Implicit Favorite

An often unrecognized bias towards a person or option that influences decision-making and judgment without conscious awareness.

Alternatives Sequentially

The process of considering and evaluating different options one after another in a systematic order.