Why Does the Isoleucyl-TRNA Synthetase Use Two Types of Proofreading

question 15

Multiple Choice

Why does the isoleucyl-tRNA synthetase use two types of proofreading mechanisms to ensure its accurate aminoacylation?

• A)It is not a very precise enzyme.
• B)It is a very big enzyme.
• C)Isoleucine is very hard to distinguish from valine,since they differ only by a single methylene group.
• D)Isoleucine is very difficult to distinguish from glycine.
• E)Isoleucine can spontaneously turn into phenylalanine.

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