Which of the Following Statements About Negative Selection During Lymphocyte

question 5

Multiple Choice

Which of the following statements about negative selection during lymphocyte development is most accurate?

• A)The mechanism of negative selection is the death of cells whose antigen receptors are not stimulated by self antigens.
• B)The mechanism of negative selection is apoptosis actively induced by antigen-receptor recognition of self antigens.
• C)Negative selection ensures a self MHC restricted repertoire of T lymphocytes.
• D)Negative selection occurs only in T cell maturation and not in B cell maturation.
• E)The major mechanism of negative selection is inhibition of antigen receptor expression.