Genetic Studies Have Identified More Than 40 Genes That Show

question 2

Essay

Genetic studies have identified more than 40 genes that show allelic variations associated with the development of allergic asthma and atopic dermatitis, as well as the predisposition to develop allergies to particular antigens. Among these genes are several that implicate CD4 T cell responses in the development of these allergic diseases. Name two genes (or gene clusters) associated with atopic diseases that indicate a central role for CD4 T cells in these diseases.

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Definitions:

Neutral

Not favoring any side in a dispute, contest, or situation; unbiased or impartial.

Unconditioned Stimulus

A stimulus that naturally triggers a response without any need for prior learning.

Stimulus Discrimination

The ability to differentiate between a conditioned stimulus and other stimuli that have not been paired with an unconditioned stimulus.

Organism

A living entity capable of growth, reproduction, and often response to external stimuli, ranging from single-celled forms like bacteria to complex multicellular entities like humans and plants.