In Mice, an Allergic Response in the Airways Can Be

question 6

Multiple Choice

In mice, an allergic response in the airways can be induced by systemic immunization with a protein antigen (chicken ovalbumin) in an adjuvant that promotes Type II immune responses, followed by several exposures to aerosolized ovalbumin administered via the airways. Mice that have a genetic deficiency in expression of the receptor c-kit are resistant to this disease because:

• A) They are unable to generate an IgE antibody response to ovalbumin.
• B) They lack expression of the high affinity IgE receptor.
• C) Their inflammatory cells do not respond to chemokine receptor stimulation.
• D) They lack mast cells.
• E) They lack B cells.

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Definitions:

Contractions

The action of muscle fibers shortening or tensing, which can produce movement or apply force, a fundamental process in muscle function.

Sarcoplasmic Reticulum

A specialized type of smooth endoplasmic reticulum found in muscle cells, involved in calcium storage and release for muscle contraction.

Active Transport

The movement of molecules across a cell membrane from a region of lower concentration to one of higher concentration, requiring energy.

Muscle Hypertrophy

The increase in muscle size and mass due to exercise, particularly strength training.