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Oral Inoculation with Rotavirus, an Intestinal Pathogen, Induces Adaptive Immune

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Oral inoculation with rotavirus, an intestinal pathogen, induces adaptive immune responses that are initiated in gut-associated lymphoid tissue, such as mesenteric lymph nodes and Peyer's patches. The rotavirus-specific effector T cells that are generated in this response are never found in the circulation, but home directly from the lymphoid tissue to the epithelium without ever leaving the intestinal environment.


Definitions:

Aversion Therapy

A behavioral treatment method that uses negative stimuli to reduce the appeal of undesirable habits or behaviors.

Operant Conditioning

The learning of voluntary behavior through the effects of pleasant and unpleasant consequences to responses.

Unpleasant Stimulus

Any object, event, or situation that is undesirable or discomforting to an individual, often leading to avoidance behavior.

Modeling

The process of learning behavior by observing and imitating others, as proposed in Bandura's social learning theory.

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