Neutralizing Antibodies Are Effective at Preventing Infection or Toxicity Mediated

question 30

Multiple Choice

Neutralizing antibodies are effective at preventing infection or toxicity mediated by pathogens or their toxic products. In fact, nearly all vaccines currently in use function by eliciting neutralizing antibodies. One example is the tetanus vaccine, in which neutralizing antibodies are generated against an inactivated form of the tetanus toxin (i.e., the tetanus toxoid) . The most important feature of a neutralizing antibody is:

• A) Having a high degree of multi-valency, such as being a pentamer or hexamer of immunoglobulin monomers
• B) Having high affinity for the antigen
• C) Being present at a high concentration in the circulation
• D) Being efficient at activating the complement cascade
• E) Having a long half-life in the body

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