The Pre-B-Cell Receptor Provides an Important Signal That Induces Transition $\lambda$

question 9

Multiple Choice

The pre-B-cell receptor provides an important signal that induces transition of pro-B cells to pre-B cells. An important characteristic of this receptor is that:

• A) It signals without binding to an extracellular ligand.
• B) It is composed of immunoglobulin heavy chains and the VJ region of a rearranged \(\lambda\) light chain.
• C) It is expressed at very high levels on the surface of the pro-B cell.
• D) It signals without requiring association with B-cell receptor signaling subunits, Ig\(\alpha\) and Ig\(\beta\).
• E) It signals without requiring the B-cell receptor signaling kinase, BTK.

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