Self-Reactive B Cells Can Be Eliminated from the Repertoire at Several

question 14

Multiple Choice

Self-reactive B cells can be eliminated from the repertoire at several stages of B cell maturation, including immature B cells that have already emigrated from the bone marrow into the circulation. This latter stage of tolerance induction is critical because:

• A) Not all self-antigens are expressed or present in the bone marrow during B cell development.
• B) Immature circulating B cells are more sensitive to antigen stimulation than the developing B cells in the bone marrow.
• C) Receptor editing is not a perfect process and some self-reactive B cells may fail to be eliminated in the bone marrow.
• D) Circulating immature B cells do not encounter tissue-specific antigens in peripheral organs and tissues.
• E) Immature B cells are trapped in the bone marrow by strong B-cell receptor cross-linking.

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Definitions:

Gender-Related Messages

Communication or signals that convey societal norms, expectations, and stereotypes related to gender roles and identities.

Sex Stereotyping

The act of assigning roles, behaviors, or attributes to an individual solely based on their gender.

Disruptive Behavior

Repeated actions that interrupt the normal flow of operations or activities, often causing disturbances or problems.

Parent/Child Communication

This refers to the exchange of information, emotions, and ideas between a parent and their child, influencing the child's development and emotional well-being.