The TCR and BCR Are Multi-Subunit Receptor Complexes

question 9

Multiple Choice

The TCR and BCR are multi-subunit receptor complexes. Experiments examining the synthesis and transport of these receptors to the lymphocyte cell surface have shown that the signaling subunits of each receptor complex are required for transport of the ligand-binding receptor subunits to the cell surface. One possible reason for this stringent control on cell surface expression is:

• A) To ensure that very few complete TCRs or BCRs are expressed on the lymphocyte surface
• B) To ensure that each lymphocyte expresses only a single specificity of antigen receptor
• C) To prevent surface expression of receptors that will bind ligand but fail to induce signals
• D) To prevent lymphocytes from triggering antigen receptor signaling pathways from intracellular forms of the receptors
• E) To ensure that equimolar amounts of all antigen receptor signaling subunits are produced

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