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Neutrophils Regulate the Production of Active Cathelicidins (A Class of Antimicrobial

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Neutrophils regulate the production of active cathelicidins (a class of antimicrobial peptides) by segregating the inactive propeptide from the processing enzyme that cleaves and activates it in two different types of cytoplasmic granules. These two types of granules are induced to fuse with phagosomes after ingestion of microbes, bringing the processing enzyme and the propeptide together.


Definitions:

Scatterplot

Graphic representation of each individual's scores on two variables. The score on the first variable is found on the horizontal axis and score on the second variable is found on the vertical axis.

Partialed Out

A statistical process of removing the effect of one or more variables to better understand the relationship between other variables.

Correlation Drops

Occurs when the strength or consistency of the relationship between two variables decreases, signifying a change in how closely they are related.

Original Correlation

The initial statistical relationship observed between two variables before any manipulation or control is applied.

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