B Cells Express a Complement Receptor That Binds to C3b

question 12

Multiple Choice

B cells express a complement receptor that binds to C3b cleavage products, such as iC3b and C3dg. When a B cell with an antigen receptor that specifically recognizes that pathogen also has its complement receptor stimulated because the pathogen is opsonized with these C3 fragments, B cell activation is greatly enhanced. Due to this mechanism, B cells can be activated by much lower concentrations of antigen (in this case, the pathogen) than if the antigen is devoid of complement components. This mechanism functions to:

• A) Ensure that pathogens are readily detected by the adaptive immune system before they replicate to high levels in the host
• B) Prevent B cells from being activated in response to antigens that are not pathogens
• C) Allow B cells to phagocytose the pathogen and help destroy it
• D) Induce increased rounds of B cell replication to make more pathogen-specific B cells
• E) Allow the B cell to block pathogen replication by interfering with multiple pathogen surface functions

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Definitions:

Weighted-Average Method

An inventory costing method that assigns the cost of goods available for sale based on the weighted average cost of those goods during the period.

Processing Department

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A method or process used by a company to capture, measure, and allocate costs to products, services, or other cost objects.

Conversion Cost

The combined cost of direct labor and manufacturing overheads, which are necessary to transform raw materials into finished goods.