Binding of a Water Molecule to the Zinc Ion Induces

question 38

Multiple Choice

Binding of a water molecule to the zinc ion induces:

• A) a hydronium ion to form.
• B) a large conformation change in the binding site.
• C) ionization of a his residue, which functions as a strong nucleophile.
• D) a lowered pKa for water, which leads to the formation of a zinc-bound hydroxide ion.
• E) an altered KM value.

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