Oligodendrocytes Are Cells in the Brain That Produce Myelin in the Central

question 51

Multiple Choice

Oligodendrocytes are cells in the brain that produce myelin in the central nervous system. Myelin regulatory factor (MyRF) is a transcription factor that is required by oligodendrocytes in order to produce myelin. Researchers investigated the importance of MyRF by having mice learn how to run on complex wheels (there were many gaps in the wheel thus making it difficult to run on-see graph below) .

-Mice that lacked the MyRF genes (P-MyRF (−/−) ) and mice that had functional MyRF genes (P-MyRF (+/−) ) ran on the complex wheel and their speed was recorded (see accompanying figure) . What group of mice learned how to run on the complex wheel more easily?

• A) mice with nonmyelinated axons
• B) mice with myelinated axons

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